Pneumosclerosis Muscular

Muscular pneumosclerosis: pathological basis, classification and clinical manifestations.

Muscular pneumosclerosis refers to the accumulation of collagen and hyaline scars of varying degrees of density and distribution in the intermuscular tissue of muscle groups (pericardium, diaphragm, respiratory muscles).

The existence of fibrous tissue in this area is associated with the peculiarities of the innervation of the pericardial muscle, which is why physiological remodeling of muscle tissue does not occur during inflammatory processes or injuries. As a result of fibrous degeneration of muscle fibers, some replacement of them with circulating connective tissue may occur, and the latter eventually turns into a scar. With pneumosclerosis, a perivascular interstitial form of inflammation develops with plethora of surrounding tissue, slight lymphocytic and macrophage infiltration with the formation of collagenolychenoid adhesions. The most typical lesion is the phrenic nerve and its branches, around which pronounced fibrous changes form in the connective tissue layers. Often the lesion also involves the nerve with the development of a combined disease - herpetic neuritis and muscular pneumosclerosis.