Senir-Ascher Syndrome

Senir-Ascher syndrome (SAS) is a dermatological disease characterized by the appearance of skin rashes after injury or surgery. The name is associated with the names of two scientists who first described this disease at the beginning of the 20th century - Franklin Senear and William Usher. SAS most

Saint-Ascher syndrome develops in the form of an inflammatory infiltrate under the skin of the legs and feet. May be accompanied by the appearance of lymph nodes and a rise in body temperature. If the patient is allergic, the manifestations of the disease may intensify in response to contact with the allergen.

The clinical picture of Saint-Ascher syndrome includes signs of lymphangitis: pain under the knee of the right or left leg, redness of the skin in this area, possible swelling of soft tissues, increased local skin temperature over the lesion. The patient's legs are visually shortened due to swelling.

Sudden peeling in the corners of the mouth may be a sign of Kawasaki disease - a severe form of a multifactorial systemic autoimmune disease, which is accompanied by the rapid development of inflammation of the respiratory tract, exanthema and alopecia, and fever. In many patients, the disease affects the kidneys, brain and heart. The development of these symptoms is critical to the patients' lives. After stopping taking nitrofurantoin, the rash in the mouth becomes gray-white in color.

Senira-Ascher is a rare inherited disease that is caused by a mutation in the ITPKB gene. It is characterized by the development of tumors similar to Hodgkin lymphoma, which spread throughout the body and can lead to various systemic problems. The disease was named after the scientists who first described its symptoms: French dermatologist Jean Benoit Senard and American dermatologist Walter Jones Usher.

Symptoms of Senir Asher's disease include enlarged lymph nodes, accumulation