Transaminase (Transaminase)

Transaminase is an enzyme that catalyzes the reaction of transferring an amino group from one amino acid to a keto acid. This process is called transamination.

Transaminases play an important role in amino acid metabolism. They allow the body to convert excess certain amino acids into other amino acids it needs.

The most studied transaminases are:

1. Glutamine oxaloacetate transaminase (GOT) - catalyzes the reaction between glutamate and oxaloacetate to form aspartate and α-ketoglutarate.

2. Glutamine pyruvic transaminase (GPT) - catalyzes the reaction between glutamate and pyruvate to produce alanine and α-ketoglutarate.

Elevated levels of transaminases in the blood may indicate damage to the liver or other organs. Therefore, determination of the activity of these enzymes is widely used in clinical diagnostics.

Transaminases are a group of enzymes involved in transamination reactions, which are a special type of transamination process. Known transaminitive reactions involve the transfer of amino groups (as donors of carbonyl groups) from amino acids to

Transaminases: what is it?

Transaminases are enzymes that play an important role in metabolism in the body. They catalyze the transfer of amino groups from amino acids to ketone acids, which leads to the formation of ketone bodies and other compounds. Transamination is an important process for the synthesis of proteins, fats and carbohydrates.

There are two types of transaminases: pyruvate transaminases and oxyglutamate transaminases. Pyruvate transaminase catalyzes the conversion of pyruvate (the end product of glycolysis) into alpha-ketoglutarate, necessary for the synthesis of glucose. Oxyglutamate transaminase converts glutamate to ketoacetone, which is then converted to glucose. Both enzymes play an important role in carbohydrate metabolism and provide energy to cells, especially during times of fasting or stress.

In addition, transaminases play a role in the synthesis of proteins and fats. For example, glutamate transaminase is involved in the synthesis of ketone acids, which are then used for energy production. Transaminases are also involved in the production of collagen, a protein necessary to maintain the structure of skin, bones and muscles.

In general, transaminases are important enzymes that are involved in various metabolic processes in the human body. Knowledge of their functions can help in understanding and controlling metabolism and diseases associated with its disorders.