Extogenic jaundice is an acute or chronic hepatitis of an infectious nature (viral or bacterial), in which the proteins of the sclera and skin turn yellow, and obstructive jaundice develops.
Everything in the body is colored with bile. The bile ducts act as a delicate drainage system. If one of the branches is clogged, other vessels do additional work. From the liver, a large amount of bile immediately enters the intestines and is just as quickly destroyed by bacteria in it. Most of the bile goes to the intestines after disinfection in the liver. There is a special barrier between the liver and intestines - the mucous membrane (lowly degradable). Entering the blood through the intestinal walls, most of the bile pigments again reach the liver - the substances are separated from hemoglobin under the influence of the protein albumin. Alloxan damages liver cells, increasing enzyme production and phagocytosis.
In healthy people, the pigment is constantly formed in the body, but enters the bile through the bloodstream. In this case, the pigment is evenly distributed throughout the blood. With jaundice, excess levels occur. Deviations are associated with the following factors:
Intoxication (chemical poisoning) Oxygen deficiency (due to low blood pressure)