Colitis Medicinal

Drug-induced colitis

(p. medicamentosa).

Introduction.

Drug-induced or drug-induced colitis is called because it predominantly “causes” inflammation of the colon mucosa when the rules for taking any medications are violated. This pathological condition accounts for 25 to 35% of cases in surgical practice. Drug-induced colitis is especially common in children. Most often this is due to a violation of the dosage regimen and interactions of drugs prescribed to the child. Without treatment, drug-induced colitis can become chronic, but timely consultation with a doctor and proper treatment in the vast majority of cases leads to recovery. In a chronic course, the process can spread to all parts of the large intestine. As the disease progresses, it leads to the formation of peptic ulcers and necrotic areas. The most dangerous complication is perforative colitis. The exact cause of its occurrence is still unknown. Drug ulcers are trophic ulcers, they appear from above, a few days after colitis, and can be multiple, point-like, randomly located, merging during bowel movements . But the pain is practically not expressed. . A painful tear of the mucous membrane is characterized by the appearance of a severe pain syndrome, which develops gradually and lasts from several seconds to several minutes. The pain is predominantly localized throughout the abdomen, has dull, sharp paroxysmal pain, “dagger-like”, radiating to the groin, perineum, sacral area, and is of a reflected nature. Colicky attacks of pain often occur for several days, then subside, periodically appear again, intensifying after the transition to the active stage of the process (during the period of diarrhea). Many patients are also characterized by the occurrence of muscle, sometimes convulsive, syndrome. Symptoms of dehydration increase - general weakness, lethargy, drowsiness, dry mucous membranes and skin. False urge to stool, leading stool