Exostoses Osteocartilaginous Multiple

Exostoses Osteocartilaginous Multiple: A Detailed Review

Osteochondral exostoses multiple, also known as aclasia diaphyseal, chondrodysplasia deformans, chondromatosis externa, cartilaginous exostoses multiple or Ehrenfried's disease, is a rare genetic disorder that affects the development of bones and cartilage. In this article we will look at the main aspects of this disease, its symptoms, diagnosis and possible treatments.

Multiple osteochondral exostoses are characterized by the formation of multiple tumors, called exostoses, on the surface of bones and cartilaginous tissues. These tumors usually arise in periosteal tissues such as the periosteum and epiphysis and may be attached to the underlying bone by a stalk or neck. Exostoses typically have a structure similar to bone tissue and can cause a variety of problems, including pain, deformity, and functional limitations.

Symptoms of multiple osteochondral exostoses can vary depending on their location and size. Some patients may not experience any symptoms, especially if the exostoses are small and do not put pressure on surrounding tissue. However, in the presence of large or multiple exostoses, pain, joint stiffness, limitation of movement, and cosmetic deformities are possible.

Diagnosis of multiple osteochondral exostoses includes a visual examination, the patient's medical history, and additional examination methods such as radiography, computed tomography (CT), and magnetic resonance imaging (MRI). These methods make it possible to determine the size, number and exact location of exostoses, which helps in planning treatment measures.

Treatment of multiple osteochondral exostoses depends on the symptoms and their severity. In some cases, if the exostoses are not causing any problems, no active treatment is required and patients can simply be monitored for changes. However, if there is pain, deformity, or other limitations, surgery may be necessary. The goal of surgery is to remove exostoses and restore normal anatomy and function of the affected tissues.

Although osteochondral multiple exostosis is a rare disease, research and development in this area continues. Some studies indicate the possibility of gene therapy or pharmacological approaches to control the growth of exostoses. However, further research is needed to fully understand the molecular mechanisms and develop effective therapeutic strategies.

In conclusion, osteochondral multiple exostosis is a rare genetic disorder characterized by the formation of multiple tumors on the surface of bones and cartilage. Symptoms may vary, and diagnosis involves visual examination and additional testing. Treatment is based on symptoms and may include observation, surgery, or potential future therapeutic approaches. Despite limited knowledge in this area, research continues to better understand and manage this rare disease.

Exostotes are outgrowths above the surface of the skin in the form of cones. Such protrusions resemble small cauliflower inflorescences; They are formed by the outer periosteum of bones. By their origin, exostotes are of a mixed nature and contain mainly connective tissue. Less commonly, the periosteum forms only small outgrowths.

In surgery, some of the possible causes of the formation of exostoses are nodules on the patella, marginal bone growths (pads), fibrosis of the bone marrow, pathology of the epicondyle or patellar region.

Exostosis occurs in patients with the following diseases: * Inflammatory joint diseases: osteoarthritis, gonarthrosis, gout

* Degenerative-dystrophic changes in articular cartilage

* Sports overload of the body exceeds the possible recovery potential of bones and