Carbamazepine

Carbamazepine is an anticonvulsant drug used to treat epilepsy and also to reduce pain from trigeminal neuralgia. The most common side effects: drowsiness, dizziness, impaired coordination of movements; With long-term use of this medicine, liver and bone marrow dysfunction may occur. Trade name: Tegretol.

Carbamazepines are iminostilbene derivatives. They are intended for use in normal and grand mal seizures, post-stroke paralytic seizures, and a combination of different types of seizures associated with migraine. They act by inhibiting GABA receptors. Neem has effective antiepileptic and muscle relaxant effects. It is also administered for post-herpetic pain as an anticonvulsant. The dosage is set individually with a gradual increase in the amount of the drug until the desired effect is achieved. Also used in psychiatric practice to relieve psychomotor agitation. In this case, the daily dose is calculated for each patient individually. A special group of patients consists of patients with impaired liver function. To achieve the desired effect, the dose is adjusted taking into account the state of the functions of the hepatic tract. Side effects of carbamazepine include drowsiness, confusion, decreased level of consciousness, tinnitus, involuntary salivation, swallowing disorders, and dizziness. Sometimes there is a deterioration in visual acuity, changes in facial features or distortion of visual perception. Nausea is considered a common side effect. Defecation disorders often occur. Cardiovascular disorders and orthostatic hypotension may develop. Rarely, elevated levels of liver transaminases and biliary tract dysfunction develop. In terms of platelet-vascular hemostasis, an increase in bleeding time is observed. In some cases, disorders of bone marrow hematopoiesis develop. Using large amounts of carbamazipine can lead to the development of hepatitis. The possibility of its progression cannot be ruled out either. Carbamazepine drugs, among other drugs in the group, more often cause idiosyncratic reactions. Among them, an increase in the level of creatinine in the blood was noted. Less frequently observed are the development of hearing impairment and intellectual disability. Indications for the use of carbazepine medications are benign hyperkinesis and trigeminal neuralgia. They are also used in the treatment of withdrawal symptoms and migraines.

Carbamazepine (trade names Carbanil, Tegretol, Zagretol) belongs to the group of carboxanenyl derivatives. This group of drugs, along with phenytoin and phenobarbital, are drugs on the list of the most dangerous in terms of the development of side effects. The effect of the drug on the body has been studied