Spicular cells are found in the epidermis of the skin of the face and upper body in humans. They are proliferative cells with a large irregularly shaped nucleus and light chromatin, short cytoplasm with inclusions of glycogen, vacuoles and single-membrane vesicles. The spinous cells are located in the stratum basale, the deepest layer of the epidermis.
The main function of spinous cells is to regulate the wound healing process: they create new skin over damaged skin. During the healing process, the spiny cells combine with keratinocytes (mononuclear cells that produce keratin, which gives the skin its basic appearance) and form new keratinocytes, which create a new layer of skin over the scar. This process is called connective tissue formation and takes from several weeks to several months, depending on the size of the damaged area.
Spine cells are also involved in other physiological processes, including the immune response and the maintenance of homeostasis (homeostasis is the body's ability to maintain a constant internal environment, such as body temperature).
In a medical context, spiny cells can be used as an indicator of immune responses in the body. For example