Colicinogenia

Colicinogeny is the hereditary ability of microorganisms of the genus Escherichia (Escherichia coli) to produce substances called colicins, which inhibit the growth of other representatives of this genus. Colicins are protein molecules that can be either endogenous (produced by the body itself) or exogenous (coming from outside).

Colicinogeny can be observed in many species of Escherichia microorganisms, including strains that cause food poisoning, diarrhea, and urinary tract diseases. Colicin activity may be beneficial to the host as it promotes protection against bacterial pathogens that cannot grow in the presence of colicins.

However, if colicinogenic strains are present in the environment, they may pose a threat to human and animal health. For example, colicins can cause illness in newborns, debilitated people, and immunocompromised people. In addition, colicinogenic bacteria can cause various diseases such as colienteritis, coliencephalitis and colytyphoid.

To combat the colicinogenic activity of bacteria, various methods are used, including the use of antibiotics, as well as the creation of bacterial strains that do not produce colicins or produce them in smaller quantities. However, these methods are not always effective, and therefore the search for new approaches to combating colicins remains an urgent task for scientists and practitioners.



Colicinogeny is the hereditary ability of bacteria of the species Escherichia coli to produce coregins - antibacterial substances that can protect the host cell from pathogenic microorganisms, which are called “antibiotic-resistant”. Colicins act as additional “guards”, preventing the development of infectious diseases.

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