Krause Skin Grafting

Krause transplantation is an effective treatment method for many diseases associated with skin damage. It involves replacing damaged or dead areas of skin with new tissue.

During the procedure, the doctor removes diseased tissue and replaces it with donor tissue. Donor tissue can be taken from the patient's body, or special artificial materials can be used. For example, for burns, the most effective method would be to use the patient's own skin for grafting. If it is necessary to cover more serious wounds, special materials or skin from the patient’s tissues surrounding the donor site are used.

Skin grafting can be used to restore damaged surfaces of the face, arms, legs and other parts of the body. However, the process of skin grafting is considered a complex procedure, requiring the experience of the surgeon and performing his manipulations accurately and with maximum attention. In addition, the graft takes time to heal. It takes several months to replace the damaged area.

Krause, August Johann Hermann Nikolaus Krause (German: August Johann Hermann Nikolaus Krause; November 12, 1846, Bruchmühlen, Lower Saxony - April 3, 1925, Stuttgart, Baden-Württemberg) - German surgeon, neurologist and founder of "clinical medicine".

It was he who created the technique of skin transplantation from the patient’s legs to the forehead and cheeks of the face. His operation set a new longevity record: the patient lived another 17 years with new skin. The hereditary doctor August Krauses began studying chemistry and pharmacology at the University of Edinburgh at the age of 15, and by the age of 16 he came under the wing of the main Edinburgh specialist in anatomy, preparation and surgery, Francis Guy. During that period, the formation of K.I.A. began. Paul Ehrlich and Ernest Rutherford, who studied the problems of immunity. In the early 1870s, 5 years of correspondence with the London luminary surgeon John Freeman of Royal London inspired Crouse to create his own skin grafting technique. The professor bequeathed £50 to the scientist to continue his work on improving plastic surgery techniques. He managed, by examining the skin on corpses, to elucidate the structure and anatomy of soft tissues and to invent a method of transplanting an excised skin flap from the forehead to the face without tension, introducing it into clinical medicine. The patient was 46-year-old Elizabeth Boling. Kraus performed the first skin graft operation on a patient in November 1902. He transferred a large array of square patches of frontal and buccal skin from the forehead and cheeks to the patient's lower face. The tone of this area of ​​the upper lip, cheek and chin deteriorated, but the entire neck remained “very normal.” As a result of this operation, the length of the lower lip and the height of the lower jaw decreased, new wrinkles appeared in the forehead, bridge of the nose, lower cheeks, neck and chin, and the skin became significantly thinner. This affected the patient’s facial expression, her mood, facial expressions and behavior. In parallel with the patient’s general malaise, the deterioration of wound healing at the donor sites, blood pressure increased, the percentage of cholesterol and bile in the blood increased, and reactions were impaired. The patient had an exacerbation of pain during and after exercise; she periodically walked with her arms down and her head tilted down. From December 1911 to August 1974, the patient stopped reacting to the environment and making basic movements, stopped contacting people around her, and after a few months stopped eating, to the point that saliva was dripping from the corners of her lips. For several long months, the patient’s “moon-shaped” face was hidden from others by a medical mask. Describing that patient in December 1996, Professor Daniel Rolet from the Jean-Enel surgical clinic in France noted her unique appearance.