Mendelssohn Syndrome

Mendelssohn-Faria syndrome was discovered and named after two surgeons, Carl Ludwig Mendelssohn and Marian Faria. It manifests as multiple organ failure that occurs after general anesthesia using inhalational agents containing nitrous oxide (N2O) and fentanyl or its derivatives

Mendelssohn syndrome is a rare hereditary disease in which the baby has a “temporal” type of dystrophy, manifested by cerebellar hypoplasia, paralysis of the facial nerve and swallowing reflex, changes in cranial nerves II, VI and VII pairs, as well as the central gyri and substance of the brain. The pathology was first described in 1932 by American anesthesiologist and American pediatrician Charles Mendel.