Panniculitis Migratory Nodular

Panniculitis or migratory nodular panniculoperiostopathy (MUPP) is a chronic disease of the skin and subcutaneous tissue, characterized by an inflammatory process and the recurrent appearance of painful compactions of various sizes and shapes in the dermis and popliteal tissue, located mainly on the extensor surface of the limbs and on the torso.

The term “panniculitis” arose as a result of anamnestic connections of this disease with diffuse panniculitis, first described by Abel Jacob in 1861. Panniculosis is a lesion of adipose tissue located in the hypodermis. As a lumpy subcutaneous formation develops, this disease is called panniculoid or panniculus. When the dermis is affected, called panniculitis, the disease appears in the medical literature under the concept of panniculia.

The process leading to the formation of pannicula or other clinical forms of migratory nodular panniculitis (MUP) is immune mechanisms, however, a clear causal relationship between the disease and an imbalance of the immune system has not been identified. It is possible that in some forms of the disease the body's defenses may be noticeably reduced and increased activity of the immune system provokes an active autoimmune process in the subcutaneous

Panniculitis migrans nodosa (PMU) (from the Latin pancreas - pancreas and -itis - inflammation) is a rare inflammatory disease of the subcutaneous fat, often accompanied by abdominal pain. Localization of PMU: Facial skin, sometimes up to the elbows and knees. It occurs in both women and men. Caused by Epstein-Barr virus Data