Schultz-Daila Reaction

The Schultz-Dale reaction (Schultz-Dyle reaction) is a physiological process that was discovered in 1897 by William Schultz and Nathan Dyle. This process describes how the brain responds to changes in blood glucose levels.

Schultz and Dyle studied the effect of glucose on the activity of nerve cells in the brains of rats. They found that as blood glucose concentrations increased, nerve cell activity increased. However, when glucose concentrations drop, nerve cell activity also decreases.

This process was called the Schultz–Dale reaction because Schultz and Dale were the first to describe it. Schultz and Dyle also showed that this process is important for regulating glucose levels in the body.

Today the Schultz–Dyle reaction is one of the most studied processes in physiology. It is used to understand how the brain controls blood glucose levels and how this control affects human behavior and health.



Schultz-Dale reaction is a rare condition of physiological influence in which individual or all organs lose the ability to reflexively contract in response to the influence of certain receptor stimuli. This syndrome was first described in 1912 by two British scientists - Wilhelm Schultz and Nicholas Dale. Due to the rarity of the phenomenon, the pathology became known much later. The condition is observed in people of both sexes, at any age, starting from the first days of life. In half of the cases the disease is hereditary. The syndrome affects any organs and systems of the body, which is why the disease is called multisystem.