Xanthofibroma

Xanthophibratoma is a soft tissue tumor that consists of benign smooth muscle cells and oxyphilic pigments, reflecting the bile pigment carried by these cells. This term is defined in ICD-10, but a similar neoplasm is described in 4 volumes of histology according to Robbins with the names “xanthoma”, “nigra fibromatous dystrophy” and some other terms.

This rare neoplasm of the skin and soft tissue primarily occurs in men, although it can also be found in women. The pathology occurs in childhood or adolescence, debuting between the ages of 2 and 40 years (on average at 30). The powerful manifestation of the pain reaction after injury is explained by the high sensitivity of the neoplasm to trauma. In some patients, subcutaneous neoplasms are accompanied by the appearance of triads: chills, pain, and decreased blood sugar. Xanthoma can be single or multiple. Common forms are giant lesions (several centimeters in diameter) containing fat that grow into the soft tissue of the forearms or buttocks. The disease is often detected as a painless and soft node, which subsequently increases in size and pain sensitivity. Diagnosis of multiple