Amanitotoxin

Amanitotoxins (lat. Amanitotoxinae) are a family of toxins produced by some mushrooms of the genus Amanita, for example, fly agarics.

Amanitotoxins contain various peptides and polypeptides, which can be either protein or glycoprotein. They have neurotoxic properties and cause various symptoms of poisoning in humans and animals.

The most commonly poisonous mushrooms are Amanita phalloides, Amanita virosa and Amanita muscaria, as well as some other species. Poisoning with these mushrooms causes disturbances in the functioning of the central nervous system, gastrointestinal tract, liver and kidneys.

Symptoms of poisoning from mushrooms containing amanitotoxins can vary and depend on the dose the person took. They usually begin with headache, nausea, vomiting, diarrhea, loss of consciousness and seizures. In severe cases, death is possible.

Amanitotoxins are not currently used for medical purposes, but research is ongoing. Some scientists believe they may have potential for treating various diseases, including cancer and liver disease.

Amanitotoxins are toxins contained in some species of laticifers belonging to the genus Amanita (lat. Amanita), which belong to the fly agaric family. The name "amanitosis" is used (from the Latin term amano - to intoxicate) to refer to the special poisoning caused by these mushrooms. A distinctive feature of many toxins of this family is their ability to enhance the effect of psychoactive substances without the participation of cholinergic receptors and thereby create the impression of mild intoxication. The content of amanitium (the substance was named after the place of discovery - the city of Amana (India)) was first established by D. Singh as a result of conducting pharmacological experiments to clarify the role of amphetamine-type compounds in the action of fly agaric. The following substances are described. Erythravirine