Neuromyelitis Optica, Devic S Disease

Neuromyelitis of the optic nerve, also known as Devic's disease, is a rare but serious disease of the central nervous system. This disease is closely related to multiple sclerosis, although it has several distinctive features.

Typically, the disease occurs in the form of myelitis, which causes paralysis and dissociated sensory disorders of the lower extremities and trunk below the affected area of ​​the spinal cord. Also a characteristic symptom is retrobulbar bilateral optic neuritis. Myelitis and retrobulbar neuritis can develop simultaneously or several days or even weeks after each other.

One of the most serious aspects of Neuromyelitis Optic Nerve is that recovery from the first attack of the disease is often incomplete. Relapses are less common than in normal multiple sclerosis, but the prognosis is poor and the disease is often fatal.

Unlike multiple sclerosis, Neuromyelitis Optica is characterized by the presence of antibodies to aquaporin-4, which is a protein found on the surface of cells surrounding nerve fibers. This leads to inflammation and degeneration of the myelin of nerve fibers, leading to symptoms of the disease.

Diagnosis of Neuromyelitis Optic Nerve includes magnetic resonance imaging (MRI) of the brain and spinal cord, as well as a blood test for the presence of antibodies to aquaporin-4.

Treatment for Neuromyelitis of the Optic Nerve includes glucocorticosteroids and immunomodulatory drugs. However, despite treatment, the prognosis of the disease remains poor, and disability often progresses.

In conclusion, Neuromyelitis of the Optic Nerve, or Devic's Disease, is a rare but serious disease of the central nervous system that has several distinct features from multiple sclerosis. Although treatment is available, the prognosis of the disease remains poor and the disease is often fatal.

Neuromyelitis optica and Devic's disease are closely related selective inflammatory lesions of the posterior column of the spinal cord and the optic nerves.

The disease affects young people, more often middle-aged women (the average age of the disease is about 35 years); In women, there is a predominance of this pathology. There are various names for this disease, including inflammation of the optic nerves and optic neuropathy.