Chronic paranephritis occurs as a result of ascending infection of the kidneys. This condition is preceded by tubulointerstitial nephritis, latent or clinically pronounced. This group includes acute pancreatitis and exacerbation of chronic pancreatitis, the symptoms of which are so severe that the likelihood of developing this complication is beyond doubt. In such cases, we can talk about the toxic-allergic nature of paranephritis: with rheumatism, chronic brucellosis. However, there is no doubt that paranephritis refers to infectious diseases of the genitourinary system, which is facilitated by the “hematogenous” and lymphatic routes of spread of infection. In most patients the process is primary. Among the common causes of secondary paranephritis are urolithiasis, dystrophic changes in the detrusor of the bladder and ectopia of the urethra in women, diverticula, adenomas and urethral strictures.
Chronic pancreatitis is a common disease that causes paranephitis to appear after 40-50 years. The pathogenetic basis of paranephritis in pancreatitis is the accumulation of tryptophan amides in the interpelvic spaces of urine