Thrombocythemia (Thivmbocythemia)

Thrombocythaemia: causes, symptoms and treatment

Thrombocythaemia is a rare blood disease characterized by abnormal proliferation of cells that form blood platelets (megakaryocytes). As a result, the total number of platelets in the blood increases significantly, which can lead to an increased tendency to form blood clots and cause the development of thrombosis. On the contrary, with thrombocytopenia the number of platelets may be reduced, in which case the person has a tendency to bleed.

The causes of thrombocythemia are not fully understood. However, it is known that this disease is associated with mutations in genes responsible for regulating the growth and differentiation of blood cells. Some studies have also linked the development of thrombocythemia to radiation exposure.

Symptoms of thrombocythemia can range from mild to severe. Some people with thrombocythemia may experience no symptoms, while others may have serious complications. Common symptoms of thrombocythemia are:

1. Headaches and dizziness;
2. Fatigue and weakness;
3. Feeling of heat or cold in the extremities;
4. Redness or tingling in the hands and feet;
5. Bleeding from the gums or nose.

To diagnose thrombocythemia, doctors use a variety of methods, such as blood tests, bone biopsy, and diagnostic myelography. If you suspect thrombocythemia, contact your doctor.

Treatment for thrombocythemia is aimed at reducing the number of platelets in the blood and preventing complications. For this, radiation therapy or cytotoxic drugs such as hydroxycarbamide or interferon may be prescribed. Aspirin and anticoagulants are often used to prevent blood clots.

In conclusion, thrombocythemia is a serious blood disorder that can cause serious complications. If you notice signs of thrombocythemia, see your doctor for diagnosis and treatment. Early detection and treatment can help prevent serious complications and improve prognosis.

Platelets are elements of the blood that help stop bleeding when small vessels are damaged. They form clots to close the wound and prevent blood loss. If a person has too many platelets or produces them too quickly, it is called thrombocytosis (thrombocythema).

A platelet is a blood cell that is responsible for stopping bleeding when cutting wounds. Like all blood cells, platelets are circular in shape, made up of several layers, and contain a nucleus. The structure is based on Charité bodies. The cells have an average diameter of 2-4 µm and contain 5 granules ranging in size from 1 to 2 µm. Granules are visible only with magnification, so to diagnose their presence in smears, special stains are carried out using silver salts and calcium hydroxide. Droplets of dye settle around the platelets and give their nucleus a specific “spherical” shape, reminiscent of the shape of platelets during microscopic examination of native smears according to Fonio (Sternberg coefficient is 4 h 5 mm). When studying by the indirect method and staining with etching solutions, i.e. During life, the nucleus has the shape of a biconcave disk, and the corpuscles are the appearance of thin threads extending beyond its contour (“jellyfish head”). For greater patient safety, when carrying out invasive manipulations, it is recommended to use the indirect method of studying the blood smear and immediate destruction (demolition into a funeral urn or fiery oven).

Thrombocetemia

Thrombosis is a disease in which too many blood cells (platelets) are produced. Red blood cells are needed to transport gases throughout the body. If a platelet imbalance (thrombocytopenia) occurs, you may experience an increased tendency to develop blood clots, which interfere with blood flow in your veins, arteries, and veins. Imbalances can also cause problems with blood disorders or bleeding. Unlike the treatment of thrombotic disease, treatment of thrombocytorrhea is aimed at ensuring faster removal of blood clots.

Tivanuloma or cidemuloma is one of the conditions of elevated platelet count. Thumbophilia has two main forms: primary and secondary. Primary thrombopathy develops in case of failure of the immune system (allergic purpura. This is a form of the disease), with hyperplasia of the red bone marrow causing a neoplastic reaction, or as a consequence of a special thrombin infection, as well as in