Chorionepithelioma, Choriocarcinoma

Chorionepithelioma, Choriocarcinoma - a rare type of cancer originating from the most distant parts of the embryonic membrane (chorion) from the center. Chorionepithelioma is a malignant tumor; it usually accompanies the development of chorionadenoma, although it can also occur after a previous abortion or even in the case of a normal pregnancy. The tumor quickly affects the lungs. It is relatively sensitive to treatment with cytotoxic drugs.

Chorionepitheliomas and choriacarcinomas are rare types of cancer that originate from the most distal parts of the embryonic membrane (in this article we will talk about choriocarcinoma).

Chorionepitheliomas can cause serious complications during pregnancy and childbirth. These tumors most often occur in women over 40 years of age, suggesting a link between maternal age and risk of developing the disease. It is believed that the risk group also includes smokers. Chemotherapy can stop the growth of chorionepitheliomas in pregnant women. Treatment of chorioepithelyomomas consists of chemotherapy during pregnancy and aspiration of amniotic fluid after 20 weeks. It is important to note that chemotherapy can cause side effects in the unborn child.

Chorionepitheliomas (CE) and choriocarcinomas (CC) are rare tumors that arise from the embryonic membrane most distant from the body - the chorion. They make up less than 2% of all malignant neoplasms in women and are one of the most dangerous types of cancer, as they affect the lungs and spread throughout the body. These tumors are epithelial cancers that are characterized by aggressive behavior and cannot be treated using standard treatment methods. This happens because this malignant tumor has pronounced proliferation properties. CE and CC are also difficult to diagnose in the early stages and have a high rate of metastasis to other organs. In this article we will look at the features of these tumors, the causes of their occurrence, clinical manifestations and treatment methods.

1. Chorionepitheliomyelosis. Chorionepithelioma is a mixed tumor that has two layers - the trophoblast, which originates in the rudimentary rudiments of the corpus luteum of the uterus, and the malignant sinus, consisting of cells located in the wall of the uterine cavity. The most aggressive and malignant cells are contained in the latter - in the blue layer. This mixture contains the mother's sex chromosomes, which produce hormones. Trophoblastic cells form small lesions that resemble blisters. When the bladder ruptures, a vascular structure appears around it, allowing it to supply the tissue and resist dystrophy. It is this move that is a consequence of the formation of the fetal yolk sac. Large lesions in the capsules lead to the migration of red blood cells in the form of small hairs. The connective tissue layer holds this mixture of cells in the area of ​​the inner lining of the uterus. As the tumor develops, all elements of the system come together until a fully developed tumor with many cysts is formed.

2. Which area is affected by the tumor? First, with the growth of chorionepitheloma, areas of metastases appear both under the mucous membrane and within the se node