Dystrophy (Dystrophy, Dystrophia)

Dystrophy (Dystrophy, Dystrophia) is a pathological condition that manifests itself in impaired development of organs and tissues, most often muscles. It occurs due to insufficient nutrition of the tissue, which leads to its degeneration and deterioration of functions.

The term is widely used in medicine to refer to several diseases, including muscular dystrophy and adiposogenital dystrophy (dystrophia adiposogenitalis), which is also known as Frohlich syndrome.

Muscular dystrophy is the most common type of dystrophy, in which there is a gradual deterioration of muscle tissue and a decrease in their functional activity. This leads to weakness, muscle atrophy and limited movement. Muscular dystrophy can be hereditary or acquired, and it can appear in different forms and degrees of severity.

Adiposogenital dystrophy (Frohlich syndrome) is a rare genetic disease in which the function of the hypothalamus and pituitary gland is disrupted, which leads to metabolic disorders and the development of obesity. Patients with this syndrome may also have delayed sexual development and other endocrine disorders.

Treatment of dystrophy depends on its type and the reasons that caused it. In the case of muscular dystrophy, for example, physical therapy, exercise, and special medications may be used to maintain muscle function. In the case of adiposogenital dystrophy, hormonal drugs and surgical methods can be used.

Thus, dystrophy is a serious pathological condition that can lead to various dysfunctions of organs and tissues. Early detection and treatment of this disease can reduce its severity and improve the prognosis.



Dystrophy is a violation of tissue development due to insufficient nutrition. In medicine, this term can refer to several diseases, the most famous of which are muscular and fatty degeneration. Dystrophic changes can occur in any tissues and organs that need proper nutrition and functioning. Violation of this system can lead to serious consequences, so it is important to diagnose and treat these diseases in a timely manner.

One of the most common types of muscular dystrophy is **Duchenne dystrophy.** This is a genetic disease that affects men, but manifests itself in women as big cutis, persistent eyelashes and polyuria. Characteristic symptoms of Duchenne dystrophy are:

1. Prolonged fatigue; 2. Lethargy; 3. Anxiety. 4. Feeling of weakness in the muscles. 5. Deformation of the limbs and chest. 6. Work heart failure. 7. Painful urination. 8. Problems in mental development. 9. Speech disorders. 10. Dyspnea and sleep apnea. Dystrophy occurs when there is a mutation in the gene that is responsible for the production of the protein dynein. This protein regulates muscle contraction, but when its quantity decreases, the muscles stop contracting and become weaker. Dynein also affects coordination of movements, so with this form of dystrophy, patients experience difficulty walking and performing normal physical exercises.

Another form of dystrophy is **muscular dystrophy



Very often we hear about various diseases and disorders in the human body. One of these problems is dystrophic pathology. What is dystrophy? In simple words, this is a violation of the development of organs and tissues of the body, most often muscles, as a result of their insufficient nutrition, and this also affects the work of other organs.

Depending on the affected area, dystrophic pathologies can be of a different nature. For example, most muscle tissue disorders are called “muscular dystrophy.” This may be a congenital, genetically determined pathology, for example, dysplasia or neurosensory, combined or other. Also, causes may include developmental defects such as Von Willebrand disease, heavy metal poisoning, infections, some forms of metabolic disorders, chronic infectious diseases, etc.

Typically, muscular dystrophies are characterized by gradual development and a set of progressive symptoms, which may include muscle weakness, pain in the extremities, sensory disturbances, decreased activity levels, muscle atrophy, and others. In some cases, symptoms may appear very gradually, and sometimes the onset of the disease may be acute. Some patients live for long periods of time without knowing that they have a disease, which is why valuable time is lost for therapy and prevention of complications.

Adiposogenital, or Adiposogenital dystrophy, is a condition in which the normal development of the gonads is disrupted. The disease was described in 1876 by Richard Leibohl Freidrich, a Dutch dermatologist. The causes of the development of the disease include heredity and infections of the genitourinary system. The doctor wrote about this disease, referring to pathological changes in the body under the influence of excessively oily secretions released from the genitals. Thus, the patient is characterized not only by problems with the genital organs, but also by the formation of areas of unhealthy fatty tissue. Clinical symptoms of such a deviation from the norm are considered to be underdevelopment of the penis, hypophalic insufficiency, inflammation and abnormalities of the genital organs, testicular oligoasthenia, the formation of excess fat deposits on the face, the formation of gynecomastia, and excess formation of the tip of the nose.

The disease can most often be determined at an appointment with a geneticist, pediatrician, or neurologist. The doctor decides a number of issues regarding the necessary research methods. Extensive blood tests, urine and blood tests are performed. A great help in diagnosis has been the study of the amount of protein and muscle cytochrome in human sweat streams, which makes it possible to identify nutritional imbalances. In studies using nuclear magnetic resonance, it is possible to obtain images of human muscles and “read” the structure of the affected elements. MRI (magnetic resonance imaging) allows you to determine the degree of damage to muscle tissue that has already manifested itself externally. Moreover, tests are carried out for



Dystrophy: disruption of tissue development due to insufficient nutrition.

Dystrophies are among the most common human diseases. Some of them, for example, muscle dystrophy and gastrointestinal dystrophy, often occur as independent nosological forms, others occur in some populations as clinical forms in various diseases