Hemosiderosis Transfusion

Transfusion hemosiderosis is a disease that develops as a result of multiple donor blood transfusions. In this case, excessive accumulation of iron occurs in the recipient’s body.

The reason for the development of transfusion hemosiderosis is the regular administration of red blood cells containing hemoglobin and iron. As a rule, the disease develops after transfusion of 20 or more doses of erythrocyte-containing media.

Main symptoms:

1. enlarged liver, spleen;

2. skin pigmentation;

3. heart failure;

4. liver damage (cirrhosis);

5. endocrine disorders;

6. arthralgia.

Diagnosis is based on determining the increased iron content in the body.

Treatment consists of stopping blood transfusions and prescribing iron chelators to remove excess iron from the body.

Thus, transfusion hemosiderosis is a dangerous complication of multiple blood transfusions, requiring timely diagnosis and adequate treatment.