Hypogonadism Primary

Hypogonadism is a syndrome associated with a lack of testosterone in the male body. If insufficient androgens are produced in a man’s body, then his sexual characteristics are not fully manifested - active formation of the testicles begins, and the body grows more slowly than usual. A lack of testosterone does not allow determining the sex of a newborn boy, and the presence of secondary sexual characteristics is typical for a female child.

Hypogonadism affects approximately 5% of men. At the same time, in patients with hypogonadism, sexual activity is much lower than the average for the population, so the disease is relatively more common - up to 15%. High-risk groups usually include a group of people with severe chronic diseases - malignant tumors and the presence of complex infections exposed to a high teratogenic load. The second group of patients are men with serious concomitant diseases associated with erection, prolapsed vagina and other problems. Primary hypogonadism develops either due to gonadal dysgenesis or a violation of their intrauterine development. The development of such a defect is caused by a congenital deficiency of enzymes responsible for the normal synthesis of genetic material. As a result, epigenetic control over the process of spermatogenesis or oogenesis is disrupted, which leads to the appearance of chromosomal abnormalities. Thus, the number of sperm or