Keratitis Parenchymal Diffuse

Diffuse parenchymal keratitis is an inflammation of the cornea that affects the entire thickness of the corneal stroma.

The causes of the development of parenchymal diffuse keratitis can be infections (viral, bacterial, fungal), trauma, burns, exposure to ultraviolet radiation, and various systemic diseases.

Clinically manifested by edema and infiltration (thickening) of the entire cornea, reducing its transparency. The cornea takes on a grayish tint. The patient complains of photophobia, lacrimation, pain and pain in the eye.

To make a diagnosis, biomicroscopy, fluorescein staining of the cornea, and microbiological examination are performed.

Treatment depends on the cause of the disease and includes the use of antibacterial, antiviral, antifungal drugs, glucocorticosteroids, vitamins, and regeneration stimulants. The prognosis with adequate treatment is favorable.

Parenchymal diffuse keratitis is an inflammatory disease of the anterior surface of the cornea, characterized by its dystrophic and exudative changes, the presence of subepithelial infiltrates.

The main manifestation of the development of parenchymal diffuse keratitis is the appearance of a characteristic “volcanic” or “lichen” spot, as well as degenerative changes in the form of corneal perforation. Visually, the anterior-posterior surface of the cornea acquires a characteristic reddish tint, the dense shiny corneal shaft smoothly turns into a scarring process. Cloudiness of Descemet's membrane (uneven, “umbrella”) indicates the development of stromal inflammatory foci.

The disease most often begins after viral and bacterial diseases, as a complication of hemolysis. The progression of the pathological process over time contributes to the development of degeneration of the corneal tissue; vascular deformations with the presence of pronounced accumulation of collagen. In the initial stage, the disease affects only a small area, which eliminates the possibility of a visual examination of the cornea by an ophthalmologist. At the pre-perforative stage of keratitis, when the corneal tissue has not yet been destroyed by infection, the process can pass without additional treatment and very quickly.