Monosomic [Ono + (Chromo)Som]

A monosomic is an organism or cell in the diploid set of which one chromosome is missing, which is why it becomes heterozygous. Depending on which chromosome is missing, monosomics can have different effects on the body.

For example, if the Y chromosome is missing, then the monosomic becomes an XY karyotype, which can lead to various diseases and developmental disorders. If chromosome X is missing, then the organism becomes karyotypic XX, which can also lead to various problems.

Monosomics occur naturally and can be found in a variety of organisms and cells. For example, in humans, monosomy can be caused by various factors such as radiation, chemicals or hereditary diseases.

However, monosomics can also be created artificially in the laboratory, allowing scientists to conduct research and study their effects on organisms. Monosomics are an interesting subject for study, as they can help to better understand the mechanisms of chromosomes and genetics in general.

Overall, monosomics are an interesting subject to study and could help us better understand how chromosomes and genetics in general work, and could also help develop new treatments for inherited diseases.



A monosomal set is a genetic phenomenon in which one copy of a chromosome or an entire chromosome is missing or altered. Chromosomal monosomy (CM), also called monosomic, is a type of chromosomal abnormality. In a normal biaxial (dipletic) set, each human cell contains two copies of each chromosome. Chromosome abnormalities result from disruption of the process of meiosis or mitosis, and monosomies are the most common among them. They occur in all age groups in both sexes, but most often occur in males during adolescence due to dysfunctional sperm.

Monosomies can cause various clinical manifestations, such as mental retardation, skeletal abnormalities, developmental defects of the cardiovascular system and others, and can also serve as precursors to such abnormalities as congenital heart defects that are incompatible with life. Taking into account the frequency of occurrence of these structural disorders in the human phenotype, their role and significance in the development of phenotypic manifestations from the perspective of the Zhdanva life cycle theory manifests itself differently in different individuals. Further study of its significance for a person’s mental state in the form of deviations and response thresholds and transfer to a variety of areas of practical and theoretical