Tick-borne spirochetosis

Spirochetous scabies (mite-borne)

Tick-borne spirochetosis is an acute zooanthroponotic disease from the group of rickettsial diseases, caused by the spirochete Rodentium marinum, transmitted by the bites of ixodid ticks. It mainly affects children, but cases of the disease have been described among adult men.

Spirochetes are obligate anaerobic and facultative aerobic microorganisms with a spiral or spiroid shape of long, 8-15 µm microbes that do not have mitochondria or microtubules. They all contain lipid molecules in the membrane. The shell is rarely present. An important factor in cultivation is the presence of a special membrane gel synthesized by the cells. Spirochytes have a sharp three-branched end and four acid-salt adhesins: F-pilons, Slp57, HSP47 (the presence of which is largely limited), MLK2. They can be transmitted through the lymphatic tract through manual manipulation. The development of spirochetes occurs inside macrophages and is called intracellular. Subclinical infections can be achieved by serotherapy in the presence of antibodies in the blood. Intrauterine infection in women who have recently had a hysterectomy can lead to infertility. Hemolytic anemia develops in some newborns after contact infections caused by maternal antibodies. Overcoming perinatal infection is only possible with the help of treatment in the neonatal intensive care unit, often with corticosteroids. A clinically pronounced manifestation can be either a typhus-like form (as with intestinal infections) with an increase in body temperature to febrile levels, the appearance of chills, shortness of breath and sweating. After 5-