Telangiectasia Cerebral Basal

Telangiectasia Cerebral Basal: Understanding and Perspectives

Introduction:
Cerebral basal telangiectasia (CBT), also known as cerebral vascular telangiectasia, is a rare neurological disorder that affects the blood vessels of the brain. In this article, we will review the basic aspects of TCB, including its definition, causes, symptoms, diagnosis, and possible treatment approaches.

Definition and reasons:
TCB belongs to a group of hereditary diseases that cause damage to the blood vessels of the brain and lead to their dilation and the formation of telangiectasia - small, dilated vascular formations. The main cause of TCD is associated with mutations in genes responsible for repairing and maintaining DNA integrity, such as the ATM (ataxia telangiectasia mutated) gene. This leads to the accumulation of DNA damage in the vascular cells of the brain and disruption of their normal function.

Symptoms:
Symptoms of TCB can be varied and vary depending on the extent of vascular damage and the area of ​​the brain that is affected. Some common symptoms include headaches, fatigue, seizures, ataxia (impaired motor coordination), vision and hearing problems, and cognitive and psychological impairment.

Diagnostics:
Diagnosing TCB can be difficult because its symptoms may resemble those that are not typical for this disease. Doctors may use a variety of techniques, including neuroimaging (such as MRI or CT scan of the brain) to visualize vascular abnormalities and identify areas of brain damage. Additional genetic tests may be performed to confirm the presence of mutations in the ATM gene.

Treatment and prospects:
At the moment there is no specific l