Inhibition Synaptic

Synaptic inhibition is the general name for the presynaptic (the excitation of the neuron is reduced) and the postsynaptic phase (the excitatory influence of the neuron's dendrite terminal is blocked or inhibited), which together serve to control excitation impulses.

It is important to note that inhibition is precisely a process in relation to which stimulation is a manifestation of the opposite effect. Thus, if inhibition prevents an increase in the electrical excitation of the neuron, then the effect of the opposite phenomenon, stimulation, is probably caused by an increase or increase in the concentration of the exciter material. The physiological role of inhibition is to maintain a constant level of excitation, but resting cells can also stimulate certain areas of other cells that have inhibitory functions.

The process of inhibition is very different from excitation - excitation in terms of the mechanism of its occurrence. If excitation occurs due to a temporary deficiency of passive or active processes and an uncontrolled collection of nerve impulses affecting the cell occurs, then during inhibition, inhibitory complexes are formed on the surface of the neuron, affecting the terminal structures of the axon. By definition, inhibition is associated with the consumption of the neuron's energy resources due to an imbalance in ionic equilibrium, which in turn may be accompanied by partial metabolic leakage. It can also lead to depolarization of the neuron and the subsequent development of a post-synaptic hyperpolarizing potential. In addition, post-synaptic inhibition can cause