Jaundice Hemolytic

Hemolytic jaundice is usually called a syndrome that causes jaundice of the skin and mucous membranes, which develops as a result of intensive destruction of red blood cells in the vascular bed. The source of intravascular hemolysis can be both external influences and disruptions in the circulatory system. Doctors use the terms “hematogenous”, “hemocholesic” or “hemolytic jaundice”.

**Hemoglolytic jaundice causes**

* gene pathology of blood. Effect of hemoglobin mutations. Heterozygous carriage of the beta thalassemia gene. The hereditary disease Hemoblastoma develops against the background of increased blood flow and local fluctuations in pH values ​​that occur due to oxygen therapy. Appears as a consequence of a congenital disorder of transmembrane H+ exchange, characteristic of bone tissue. Occurs in the stronger sex; * recurrent genetic damage - hereditary damage to the hemoglobin structure;

* erythrocyte defect - a change in the shape of the erythrocyte, leading to disruption of gas exchange or pathology (destruction); * hypoxia - lack of oxygen; * liver/spleen pathology - abnormalities in the functionality of the liver (hepatitis) or in the functioning of the spleen (splenomegaly); * hemodialysis with insufficient efficiency; * viral diseases - lupus erythematosus, hepatitis C, HIV infection; * poisoning. Long-term use of aspirin, sulfonamides, paracetamol

Hemolytic jaundice is a group of acute hepatopancreatobiliary diseases, the common symptom of which is severe hemolytically caused hyperbillirubinemia. These conditions are characterized not only by a high level of plasma bilirubin, but also by the presence of free bilirubin in bile with a normal or slightly increasing relative density, which also distinguishes this group of jaundices from mechanical and parenchymal forms of hyperbilirubinemia. The presence of a sign of hemolytic jaundice confirms the need for a thorough study aimed at finding the root cause of the development of hemolysis, since it can be associated with almost any systemic pathology.