Choroiditis Honeycomb Doina

Doina honeycomb choroiditis is another name for colloid retinal degeneration.

Retinal colloid degeneration is a rare inherited retinal disease that appears in adolescence or young adulthood. Characteristic features include progressive vision loss, night blindness and a narrowing of the visual field.

The cause of the disease is mutations in the EFEMP1 gene, which encodes the fibulin-3 protein, which is important for the normal structure and functioning of the retina. Pathological changes affect the retinal pigment epithelium and the choroid of the eye (choroid), which is why the name “Doina honeycomb choroiditis” comes from.

There is currently no effective treatment for colloid retinal degeneration. Genetic research and study of the mechanisms of development of the disease are being carried out in order to find treatment methods in the future.