Dyscholia Exogenous

Exocrine dyscholia is a dysfunction of the liver, which is characterized by excessive secretion of bile into the intestines. This can be caused by various reasons, such as poor diet, alcohol or medications.

With exocrine dyscholia, there is an increased production of bile, which cannot completely leave the intestines due to impaired motility of the gallbladder. As a result, bile accumulates in the intestines and can cause various symptoms such as abdominal pain, nausea, vomiting, diarrhea and others.

To diagnose exogenous dyscholia, various methods are used, including laboratory blood tests, ultrasound of the liver and gallbladder, as well as endoscopic examinations. Treatment may include lifestyle changes, diet, medications, and surgery.

However, it is important to note that exocrine dyscholia can be caused by serious liver diseases, so if symptoms appear, you should consult a doctor for consultation and examination.

Eusdogenic dyscholia.

D. is a general concept for a number of hereditary disorders of hepatic excretion of bile acids. They are characterized by a violation of the reabsorption or conjugation of these acids in the intestine or hepatocytes, with the failure of some of them to be absorbed and their entry (accumulation) into the bile ducts. This syndrome, caused by genetic defects in enterocytes, ductal proteins, or hepatic bile acid clearance, may be primary or secondary. Clinically, D. manifests itself in two forms: congenital - with signs of diffuse liver diseases and biliary cirrhosis; and acquired - with manifestations of hepatitis, impaired detoxifying function of the liver, as well as damage to joints and other internal organs. Diagnosis is difficult because the synthesis and deconjugation of bile acids is associated with many components of the metabolism of the liver itself. Therefore, the typical picture is found only in children if other metabolic pathways are not genetically damaged. A congenital defect in the binding of labeled bile acids or glucuronides secreted into the urine does not provide information about the state of the biliary tract, while the accumulation of bile is pronounced. Hepatic D. is detected in the first 6-8 weeks. life of the child, it is characterized by the excretion of labeled acidic bile pigments in significant quantities with urine and feces, the child begins to have seizures