Xeroderma pigmentosa

Xeroderma pigmentosum is a rare genetic disease characterized by increased sensitivity to ultraviolet radiation. Symptoms of this disease can appear as early as childhood and can lead to serious complications.

Xeroderma can be caused by various factors, such as genetic predisposition, sun exposure, certain types of radiation, or chemicals.

The main symptom of xeroderma is increased sensitivity to ultraviolet rays, which leads to the rapid development of sunburn and skin lesions. In addition, patients with xeroderma may experience increased skin pigmentation, which can spread throughout the body.

Other symptoms may include hyperpigmentation, red rash, dry skin and small papules. These manifestations can begin at an early age, although symptoms usually appear in adults between 20 and 40 years of age. In some cases, due to increased sensitivity to sun



Xeroderm pigmentosum

is a hereditary disease. It can appear at different ages, and its causes are not fully understood. The primary symptoms include hyperpigmentation and poor tissue regeneration as a result of exposure to sunlight. Other symptoms include tissue hypoplasia and infections. The genetic cause of this disease is a defect in active folic acid, which causes damage to the DNA of skin cells. Even low doses of solar radiation increase the risk of this disease.

People with this disease react poorly to ultraviolet radiation. Their pigmentation can be either gray or brown. When exposed to sunlight, the skin that covers the skeleton becomes darker. The body's ability to heal tissue is also reduced. Because of this, patients should not be exposed to direct sunlight for long periods of time. Pigmentation under the influence of ultraviolet radiation can appear on skin that has not been exposed to the sun. The pigmented part is also prone to fibrosis and scarring.