Blistering leprosy (leprichorosis) is a chronic and relapsing skin disease involving the immune system. It is characterized by the appearance of multiple, small, deep skin lesions that can appear on any part of the body, including the face, arms, legs, ankles, and so on. It is called pemphigus leprosy because early in the disease, patients begin to develop small red spots covered with black dots, resembling leprosy.
Pemphigus has three forms: * True pemphigus (atrophic or bullous) - with this form, small blisters appear on the skin, which break off, leaving only ulcers. Patients often have pale skin, and their gums and tongue may be infected. The true form of the disease most often develops in young people. *Rheumatic pemphigus is a milder form of pemphigus that affects only the top layers of the skin and often appears as a rash on the face and arms. * Löpper's pemphigus occurs in patients with leproma-leproma, more often as the disease progresses. It is characterized by erythema with papules on hyperemic plaques, quickly turning into a bullous form. With a long course, the disease progresses to atrophy and eczematization of the skin. Löpper's blisters are opened, but after the crusts are rejected, areas of severe atrophy usually remain.
The usual places for lesions to appear in true pemphigus are the lips (usually on the inside), tongue, cheeks, groin area, and genitals. First, small areas of skin are affected, then gradually the pustules cover the entire body. As complications, deterioration of the kidneys and liver may occur. A characteristic sign of true herpetitis bullae is that the rupture of their wall is accompanied by the release of clear fluid (positive Nikolsky's sign). Next, a serous or confluent crust forms. The period of reverse development of the disease is characterized by epithelization of only erosions, and the resulting restoration of skin thickness is uneven, which gives rise to pseudoatrophic scars.