Meningioma Meningothelial

Meningiomatosis (tumor, multiple meningioma) is a tumor process accompanied by numerous single or diffuse isolated meningeal manifestations, as well as the presence of single, multiple or diffuse meningoracomatous formations in various parts of the brain or extracerebral areas of the skull, located throughout life. It is distinguished by its steadily progressing character. Accordingly, the modern concept of meningiomatosis provides for the following stages of the disease: from the stage of development of small tumors that gradually grow, but, in fact, do not change the “clinical picture” and demonstrate the unpredictability of their further progression, to the stage with pronounced clinical manifestations. Moreover, for each patient this stage may vary in length of time. However, the progression of the disease is the same in all patients. Actually, this fact determines the relevance of a multidisciplinary approach to the problem of meningiomatic tumors [4].

The first indications of descriptions of tumors with elements of meningeal formations are found in the 16th–17th centuries. The question of their origin remained and remains relevant. Despite a fairly intensive study of the process, there is no consensus on the origin and structure of meningiomas. It has been suggested that meningeomatism can be considered as a pathological process, the cause of which was the sudden contact of adjacent brain cells and the dura mater [88].

Meningioma is a vascular tumor of the central nervous system because it arises from remnants of blood vessels or the blood-brain barrier, which is normally impermeable to blood components. Depending on which part of the vascular system is affected, there are different types of menin.