Osteopathia Hyperostotica

Osteopathia hyperostotica (from the ancient Greek ὑπέρ - over, excessively and ὀστέον - bone) is a rare hereditary disease of the skeleton, characterized by progressive ossification (ossification) of tendons, ligaments and places of attachment of muscles to bones.

The disease was first described in 1968 by American scientists Resnik and Nimon. Inherited in an autosomal dominant manner. The cause is mutations in the COL6A1 gene.

Clinically manifested from early childhood by limited mobility in the joints. Progressive ossification leads to severe disability of patients. Characterized by joint contractures, muscle weakness, and pain. Treatment is symptomatic.

Osteopathy Hyperostotic is a rare genetic disorder characterized by excessive bone growth

Osteopathy hyperostotic, also known as metaphyseal dysplasia, or Husman-Hesscharis syndrome, is a rare inherited musculoskeletal disorder.

It is usually the result of a complex series of genetic abnormalities, each of which can cause delays in the normal development of the bones of the leg and arm. These problems may begin after the baby is born, and symptoms may continue to worsen as you age. However, this is not all you need to know about Osteopathy Hyerostotic. In this article we will look at information about this disease in more detail, including the treatment of this disease.

Causes of the disease In the case of Osteopathic hyperostotic, the normal development of the bone frame is difficult for several reasons: 1) The existence of one, two or three different disorders. Symptoms can occur in any combination. 2) The long process of enlargement and branching of the bone component of the limb is a natural process that is completed by a certain age. If this process is delayed, physical problems arise. 3) Impaired absorption of calcium, phosphorus and other minerals, which causes the formation of unbalanced bone tissue. In the early stages of metabolism, calcium is deposited inside bone structures. Sometimes osteopathy of hyperplasia leads to the fact that it is deposited outside the bone tissue cells, that is, where its presence is not required. When osteoblasts (building cells) divide to build new bone mass, they secrete colonies of white blood cells into the exudate. 4) Due to abnormal bone development, the body is able to delay mineralization in one place - the bones