Sclerosis Diffuse Infantile Krabbe

Diffuse sclerosis in infancy (syndromum stuxoidum)

Congenital deficiency of growth factor of nerves (GRN), mainly of motor neurons of the anterior horns of the spinal cord and sensorimotor cortex. Under the influence of endogenous factors and external influences, the defect acquires a manifest form. The clinical manifestations of the disease are extremely varied. Along with a kind of oligophrenia, there are a variety of movement disorders, sensory disorders, and neurodynamic disorders. Psychopathic-like deviations are often observed. Infant sclerosis (Stuxen syndrome, sclerosis - rough cell syndrome) is a clinical and morphological concept that combines clinical and paraclinical pictures of a number of congenital diseases