Thrombocytopenia Autoimmune

Autoimmune thrombocytopenia is a condition in which the body's immune system mistakenly recognizes and destroys its own platelets. This leads to a decrease in the number of platelets in the blood (thrombocytopenia) and disruption of blood clotting processes.

In autoimmune thrombocytopenia, the body produces autoantibodies directed against platelet membrane proteins. These autoantibodies bind to platelets and stimulate their destruction in the spleen.

The main symptoms of autoimmune thrombocytopenia include spontaneous bleeding from the mucous membranes (nasal, gingival, gastrointestinal bleeding), the appearance of petechiae and ecchymoses on the skin.

Diagnosis is based on the detection of thrombocytopenia during a general blood test and the exclusion of other possible causes of low platelet count.

The main treatment method is immunosuppressive therapy with glucocorticosteroids and intravenous immunoglobulin. In severe cases, splenektomia (removal of the spleen) may be required. The prognosis with adequate therapy is favorable.

Thrombocytopenia of autoimmune origin. Thrombopathy does not differ from other thrombocytopenia clinically, but the addition of increased bleeding and/or loss of consciousness indicates progression of the disease. You should check with the patient whether he has had an episode of stroke. A combination of this type of thrombocytopenia with vasculitis is also noted. The most commonly recorded retinal microangiopathy is panencephalitis with intracerebral hemorrhages. Severe platelet suppression was recorded only in cases of detection of antiphospholipid antibodies in the blood [2]. The severity of clinical manifestations can vary greatly and may not even be sufficiently pronounced for diagnosis. However, when the absence of a previous stroke is combined with thrombocytopenia, after an episode of bleeding, puncture of the cerebral venous sinus and urgent use of efferent methods to prevent stroke are required in the absence of an appropriate medical history.

Thrombocytopennitia is a condition that is associated with the presence of an abnormal number of platelets in the blood. This can lead to bleeding, which can be life-threatening if not treated correctly. People with weak immune systems are more likely to develop thrombocytopenia. One of the most common types of thrombocytopenia is autoimmune thrombocytopenic purpura (AITP), which usually affects children and young adults.

Autoimmune diseases are characterized by the fact that