Bostrup Syndrome

Bostrup syndrome is a clinical and radiological symptom complex characterized by increased intensity of the shadow of organs against the background of a radiolucent tumor or affected part of the joint, accompanied by limited function. It was discovered and described by Czechoslovak scientists in 1937. Among the founders of this direction is the famous Czech trauma surgeon Professor Janus Jansky. The disease is also known as antrum syndrome and retromammary syndrome. The disease was first discovered at the age of 17, when the boy had protruding tumors in the armpit.

Bostrup syndrome is a rare congenital disease that leads to shrinkage of the knee joints and poor circulation in the legs. This syndrome occurs in children and adolescents, and is manifested first by an increase in body temperature, and then by specific symptoms.

The disease was named after the Danish radiologist Bostrup Sign, who first described it in 1926. According to him, the pathological process begins with the inner lining of the arteries, which leads to its thickening and the appearance of calcified plaques on the walls. In this condition, blood cannot flow freely through the arteries, causing pain and fever.

The first sign of the disease is usually observed in infancy - the child begins to feel severe pain in the bones and joints, which is usually accompanied by elevated body temperature. Swelling and redness of the skin around the knees are also observed. As the child grows, symptoms may worsen, to the point where the knees become thin and fragile. If the syndrome is diagnosed early enough, treatment can be conservative and includes taking anti-inflammatory drugs and analgesics. However, in cases of severe circulatory problems in the lower extremities, surgery may be required. It is important to note that the prognosis depends on the severity of the disease and the time when it was detected. Overall, Bostrup syndrome affects approximately 25 people per million of the population, with only a small percentage requiring hospitalization.