Leucoderma Lace

Leukoderma lepranguma is an example of non-neoplastic erythema of newborns with symptoms similar to chloasma, consisting of progressive depigmentation and desquamation of the eyelids and then the facial skin. The pores of the skin of the eyelids are not filled with epithelium, and therefore a mesh pattern appears (like lace).

There are congenital and acquired leukoderma leprangum. The most common causes are prematurity, maternal starvation and dehydration, maternal syphilis or asymptomatic visceral syphilis. The development mechanism is associated with pigment deficiency and atrophy of the epidermis in the areas of hair follicles. The main reason for the appearance is the transplacental movement of syphilotic infection from mother to child, along with which there is a transfer of antibodies that prevent the fixation of the main and other components of melanin. This reason is the main reason for almost all cases of congenital leukodircover.

**Clinical picture** The eyelids and facial skin are affected (see Fig. 4.60). Brown or yellowish spots appear in the affected area. In some cases, hypopigmented areas may appear. The epidermis in the area of ​​the spots atrophies, which leads to the appearance of a delicate network pattern on the eyelids and roughness of the skin under the lesions of leukoderma lepranum.

Leukodermous leprosy is usually observed during the neonatal period, but occurs in children in the first year of life and rarely in adults.