Marie-Lehrie Syndrome

Marie-Léry syndrome: Understanding and characteristics

Marie-Léry syndrome is a neurological disorder named after the French neurologists Jean-Martin Charcot (1825-1893) and Alfred Léri (1875-1930). This syndrome, also known as diffuse sclerosis, is characterized by damage to the central nervous system and affects various aspects of the patient's life.

Marie-Léry syndrome usually manifests itself as a gradual deterioration of motor skills and coordination. Symptoms may include muscle weakness, spasticity, balance problems and gait problems. Patients may also experience difficulties with speech, vision and memory. Gradually, problems arise with daily tasks such as dressing, feeding, and self-care.

This syndrome is considered rare and its causes are still not fully understood. Some researchers attribute it to genetic factors, while others suggest it may be caused by external factors and infections. The diagnosis of Marie-Léry syndrome is made based on clinical manifestations and the results of various neurological tests, such as magnetic resonance imaging (MRI) and electromyography (EMG).

Treatment of Marie-Léry syndrome is aimed at relieving symptoms and maintaining the patient's quality of life. Physical therapy, occupational therapy, and speech therapy may be helpful to improve motor skills, reduce muscle spasticity, and develop alternative modes of communication. Additional medical support and rehabilitation can help patients cope with the physical and psychological difficulties that arise.

Although Marie-Léry syndrome has no cure, early detection and prompt treatment can help slow the progression of symptoms and improve patients' quality of life. It is important to support patients and their families by providing them with social and emotional support.

In conclusion, Marie-Léry syndrome is a rare neurological disorder that has a significant impact on the lives of patients. Understanding the symptoms, diagnosis and adequate treatment play an important role in improving the quality of life of patients with this syndrome. Further Note: This description is provided in duplicate form and its contents are not current or informative. I recommend using it as a starting point and expanding it to include more detailed information about Marie-Léry syndrome, such as causes, pathophysiology, epidemiology, and current treatments.

**Marie-Lehrie syndrome**

***Marie-Lehry syndrome*** is a congenital non-infectious lesion of the child’s brain as a result of agenesis of the corpus callosum. It is also called "Marie Lery syndrome" after the French neurologists Marie Lérinne Gervais and Edwind Holden Marie. Marie Lerina was the first to describe a congenital pathology of the development of the midbrain coupled with weakness of focus VI of the superior cutaneous and motor optokiranomotor (Lerninna-Marie syndrome).

**Incidence** Marie-Lerino syndrome is 1 case per 4–7 thousand newborns. That is, this pathology occurs in approximately 1 out of 5 children. According to other sources, its prevalence is higher - 1:2-1.5/10,000

*Marie-Léry syndrome* is a rare neurological disorder that is characterized by high body temperature, persistent insomnia and mental alertness. First described by French neurologists Marie-Louise Léri and Émile Marie in 1908, the syndrome is named after two famous scientists who participated in its discovery.

The syndrome usually begins suddenly and is manifested by a significant increase in body temperature up to 40 degrees Celsius and above. At the same time, the person feels very cheerful, energetic and active, and often cannot fall asleep or relax. These symptoms persist for several days or weeks. However, over time, the intensity and duration of symptoms decrease.

In some cases, patients with Marie-Ler syndrome experience insomnia. Patients often feel that they cannot sleep, even though they would like to go to bed. They often wake up in the middle of the night to make sure they are still awake. If this is the case for them, then they feel tired and exhausted after sleep.

Patients also complain of increased mental tone. They feel that their brain works more efficiently and responds quickly to external stimuli. As a result, they often exhibit increased activity, constant mental stress and overexertion.