Landry S Paralysis

Landry S Paralysis is a rapidly progressive form of Guillain-Barré syndrome characterized by ascending paralysis starting in the lower extremities.

This is a rare autoimmune disease in which the immune system attacks nerves, causing inflammation and damage to the myelin sheaths of nerve fibers. This leads to disruption of nerve impulses and muscle paralysis.

The syndrome was first described by French neurologist Jean Landry in 1859. Hence the name - Landry's palsy.

Symptoms begin with numbness and weakness in the legs, which quickly (over hours or days) spread to the arms and other parts of the body. Sensory disturbances, breathing and swallowing problems may also occur.

Treatment primarily consists of intravenous immunoglobulins or plasmapheresis. Glucocorticoids and physical therapy are also prescribed. With timely treatment, most patients recover completely or almost completely.

Thus, Landry's palsy is a severe but treatable autoimmune disease of the peripheral nervous system that requires emergency measures to prevent disability. Timely diagnosis and adequate therapy allow achieving good treatment results.



Landry's palsy, also known as Landry's syndrome or Landry S Paralysis, is a rare but potentially fatal disease characterized by rapid progression of muscle weakness and paralysis. This is a form of Guillain syndrome, a neuromuscular disease that is usually caused by infection or other factors that cause nerve damage.

Landry's palsy begins with weakness in the legs and spreads to the upper body and respiratory muscles. In most cases, the disease progresses very quickly, over several hours or days, and can lead to complete paralysis and respiratory arrest. At the same time, sensitivity is preserved and sometimes the ability to move the eyes remains.

The causes of Landry's Palsy are still not fully understood. However, most cases are known to be associated with infectious diseases such as respiratory tract infections, gastrointestinal infections and viral infections including polio virus. Other factors such as injury, stress and certain medications are also possible.

Diagnosis of Landry's Palsy is based on symptoms and neurological examination results, as well as ruling out other possible causes of muscle weakness. Treatment consists of maintaining breathing and cardiac function, preventing complications such as urinary tract infections and circulatory failure, and providing immunomodulatory therapy that can help slow the progression of the disease.

Overall, Landry's Palsy is a rare but very serious condition that requires immediate medical attention. The prognosis depends on many factors, including the rate of disease progression, age and general condition of the patient. Although the mortality rate of this disease can be high, timely and adequate treatment can improve the prognosis and help patients cope with this serious disease.



Lanry's paralysis is a rare neurological disease that represents a selective loss of voluntary movements over the opposite half of the body. It is quite rare, has a high mortality rate and has been poorly studied, which makes it difficult to determine the causes of its occurrence and develop effective treatment methods.

It was first described in 1968 by gynecological oncologist Leslie Landry in a male doctor suffering from testicular cancer. This allowed the disease to be called Langri's paralysis. The disease is characterized by movement disorders of opposite parts of the body and is often accompanied by confusion. The disease occurs in all countries and in people of all ages. The average age of patients is 56-60 years.

Symptoms and clinical picture of the disease Lanry's paralysis S is manifested by: - ​​weakness in one limb with impairment or complete loss of its voluntary functions; - anesthesia, decreased sensitivity in the affected area. For example, the patient does not feel touch on a part of the body where the innervation is impaired; - changes in the patient’s body posture and impaired motor functions. He can tilt