Paramyeloblast

Paramyeloblast: a rare term in historical context

In medical terminology, there are many complex and little-known terms that have been used at various times to describe various conditions and pathologies. One such term is “paramyeloblastus,” which appears in historical sources but is not widely used in modern medicine.

The word "paramyeloblast" is formed by combining two components: "para-" and "myeloblast". “Para-” means “next to” or “similar,” while “myeloblast” is a term used to refer to immature bone marrow cells that precede the formation of granulocytes, a type of white blood cell.

However, although the term "paramyeloblast" has a logical meaning, its use in modern medical practice is limited. Currently, this term is not used to describe specific cells or conditions.

It is possible that in a historical context "paramyeloblast" was used to refer to some intermediate form between the myeloblast and mature granulocytes. However, the exact definition and meaning of this term requires additional research and clarification, which may be missing from modern medical sources.

In conclusion, the term "paramyeloblast" is a rare historical term that is not widely used in modern medicine. Its use is probably limited to certain historical periods and studies. Understanding its exact meaning and meaning requires further research and documentation to establish its connection to a specific condition or cells.

Myeloblasts are the most numerous representative of the cell population that makes up mature bone marrow. They precede the maturation of red blood cells, neutrophils and lymphocytes. The record holder is a rollerblade cell - 48 days. Most often, acute myeloid leukemia is diagnosed in elderly people: over 60 years of age, it occurs in 32% of cases. The favorite site of injury in the pathological process is the brain. Classification

Acute myeloid leukemia is a malignant formation that develops from the precursors of hematopoiesis - the myelopoiesis stem cell (we talked about it above). Today it is customary to use a multi-stage system of differential diagnosis of blast cells to establish the diagnosis of myeloid leukemia:

According to clinical and hematological characteristics: 70% of cases are due to the acute group, more than 80% are due to acute granulocytic myelosis (AML), 50% are AML without the Philadelphia chromosome in the cells; granulocytes less than 3x10^9/l. In children - more than 90-95%, without paired translocation t(8;21)(q22;q22) - approximately 30-32%. These cells are very similar in their biological properties, and AML is often considered a “stage” of the process of acute myelomyelologic lesions, characterized by a predominance of blasts. APM is characterized by the promyelocyte stage, and blast crisis is more often observed in AML. However, there remains a significant difference between AML and AML for pediatric patients > 5 years of age - the predominance of neutrophilic forms and the presence of granulocytosis in adult patients. In acute monoblastic leukemia, cytopenia is the predominance of monocytes in the bone marrow with a good cellular composition of the peripheral blood. In OMO, the disease begins acutely or gradually. A typical blurred picture of leukopenia is neutrophils predominate