Cholera Toxin

Cholera toxin is an exotoxin produced by the gram-negative bacterium Vibrio cholerae and is the most dangerous clinically significant product of this microorganism.

Cholera is an acute infectious disease that occurs with rapidly progressing watery diarrhea. The disease is one of the so-called “transient” ones, since in the vast majority of cases it ends in the death of patients after a few days without a previous stage of recovery. It is one of the most contagious human diseases and is spread by drinking water. In all forms of cholera, the development of bacterial carriage is possible, which can have a long course. Bacterial resistance to one of the main drugs against cholera - antibiotics - is also the reason for the long and successful evolution of the pathogen among humans.