Histidine dicarboxidase (HDD) is an enzyme involved in processes catalyzed by kinases. It is a type II glycosylphosphodiesterase. Belongs to the class of lyases. Has nine main isoforms. It is found in all tissues and organs, and to varying degrees. The largest amount of enzyme is found in the gastric mucosa and salivary glands. In the human fetus it is also found in muscle tissue in very small quantities. There is no GDD in the kidneys. It enters the kidneys only after the birth of the child. As a rule, before this age the level of the enzyme in a given tissue is negligibly low.