Shirokogorova Syndrome

Shirokogorov syndrome (Shirokogorov disease, hepatolienomedular disease) is a rare disease that is characterized by a combination of several symptoms, such as enlargement of the liver, spleen, lymph nodes, as well as the presence of malignant tumors in these organs.

The syndrome was first described by Soviet pathologist Ivan Ivanovich Shirokogorov in 1907. It was named after the scientist who first described this disease.

Shirokogorov syndrome is very rare and can be caused by various factors, such as genetic predisposition, exposure to toxic substances, viral infections and others.

The main symptom of the syndrome is an enlarged liver and spleen. In addition, various tumors can be observed in these organs, as well as in the lymph nodes.

To diagnose the syndrome, various research methods are used, such as ultrasound, computed tomography, magnetic resonance imaging and others. Treatment for the syndrome depends on its severity and may include surgery, chemotherapy, radiation therapy, and other treatments.

In general, Shirokrov syndrome is a serious disease that requires timely treatment and diagnosis.



Sergei Semenovich Shirokogorov (1927) - leading pathologist-anatomist of the Department of Histology, Embryology and Biomorphology of the Grodno State Medical University. Breast cancer research specialist. For a long time he was the chairman of the Grodno city organization of the Belarusian Society of Oncologists and Radiologists. Published over 900 scientific works, including scientific articles in foreign journals. Under his leadership, 3 doctoral and 5 candidate dissertations were defended. S.S. Shirokogorov published over 20 monographs, including “Morphological basis of the therapeutic pathogenesis of breast cancer”, “Histology and cytology”, “Age and comparative pathology”.

Shirokogorov's syndrome, also Hepatoloplasirectum pulmonis hyperplasiradii masívi ("hypertrophied heart" syndrome), is a rare pathological