Spherocytosis

Spherocytosis is a group of hematological diseases characterized by the presence of irregularly shaped red blood cells in the blood - spherocytes. These abnormal red blood cells are spherical in shape, unlike normal disc-shaped blood cells. Spherocytosis can be hereditary or develop with certain types of hemolytic anemia.

The most common type of spherocytosis is hereditary spherocytosis, which is inherited. This genetic disease manifests itself in childhood and is characterized by an enlarged spleen, pale skin and mucous membranes, jaundice and increased vulnerability to infections.

With hereditary spherocytosis, the process of formation and functioning of the spectrin protein, which ensures the stability of the shape of red blood cells and their ability to deform, is disrupted. As a result, red blood cells become fragile and quickly break down, leading to anemia.

Symptoms of hereditary spherocytosis may include fatigue, weakness, pale skin and mucous membranes, jaundice, an enlarged spleen, and frequent infections. Diagnosis is made based on clinical symptoms, blood tests, and genetic testing.

Treatment for hereditary spherocytosis includes iron therapy to compensate for blood loss, the use of blood substitutes, removal of the spleen, and bone marrow transplantation in severe cases.

Spherocytosis can also occur with certain types of hemolytic anemia, which are characterized by accelerated destruction of red blood cells in the body. In this case, spherocytosis is secondary and is caused by a violation of the membrane structure of erythrocytes.

Overall, spherocytosis is a serious condition that can lead to various complications. Therefore, it is important to promptly consult a doctor if appropriate symptoms appear and undergo the necessary examinations to diagnose and treat the disease.

Spherocytosis is a pathology characterized by the presence in the blood of red blood cells that have an irregular shape - spherocytes.

Spherocytosis is a common cause of hemolytic anemia in children and adults. In most cases, spherocytes are formed due to genetic disorders in the structure of the erythrocyte membrane. Also, spherocytes can form as a result of certain diseases, such as malaria, Wilson-Konovalov disease, glucose-6-phosphate dehydrogenase deficiency and others.

The presence of spherocytes in the blood can cause various symptoms such as jaundice, weakness, dizziness and others. If spherocytes are left untreated, it can lead to serious consequences such as kidney failure, heart failure, and even death.

To diagnose spherocytosis, a blood test must be performed to show the number of spherocytes and other forms of red blood cells. Treatment depends on the cause of the disease and may include medications, blood transfusions, or removal of the spleen.

Thus, spherocytosis is a serious pathology that can lead to serious consequences if not treated promptly. Therefore, it is important to consult a doctor at the first signs of the disease and follow his recommendations.

Spherocytosis is the general name for a number of diseases characterized by the detection of spherocytes (oval-shaped red blood cells) in the peripheral blood. It differs from sickle cell anemia only in the content of normal hemoglobin in the bone marrow. Some forms of hereditary