Transheterogeneity

Transheterogeneous is a type of genetic variation in which dominant genes with a specific locus are located both in the endogenome (inner part of the genome) and in the exogenome (outer part of the genome).

The concept of “transheterogenoto” was introduced in the 1980s as part of research into the genetic mechanisms of the development of malignant tumors. Currently, this concept is used in various fields of science, including medicine, biology, genetics and others.

Transheterogenoto can occur as a result of mutations in genes that control the expression of certain proteins involved in the development of the organism. Mutations can occur in both the exogenome and the endogenome.

One of the main problems associated with transheterogeneity is the difficulty of diagnosing and treating diseases caused by this type of genetic variation. This is due to the fact that most diagnostic methods cannot determine the exact location of the mutations, and also because the effectiveness of treatment may be reduced due to the fact that the mutations are located at multiple loci.

However, despite these problems, research in the field of transheterohemotogeotypes continues to develop rapidly, and it is hoped that in the future new diagnostic and treatment methods will be developed that will more effectively combat diseases caused by this type of genetic changes.



A transheterogenous mixture is an unusual form of mixing of hereditary factors in which the chromosomes of one of the components are contained in both genotypes of the descendants. The appearance of offspring with unique characteristics is due to genetic and epigenetic changes in the parents. Most often it occurs in a homozygous state of two different loci. Such changes are possible due to the mixing of the hereditary material of fathers and mothers in the cells of new organisms. In this case, we can talk about the presence of several forms: multiple transheterogeneity and multiple. In the first case, the genetic material of the father and mother is mixed in equal proportions, resulting in the separation of the gametes of the germ cells. In the offspring, one sex cell contains the genome of the father, and the other contains the genome of the mother. In the second case, the mixing occurs unevenly. There is a more dominant locus, transmitted exclusively from one of the parents, while others give a less significant effect.