Corneal Ulcer Creeping

Creeping corneal ulcer (u. corneae serpens; synonym hypopyon-keratitis) is an inflammatory disease of the cornea, characterized by the formation of an ulcer that tends to slowly spread over the surface of the cornea.

The disease is usually caused by herpes simplex viruses or a fungal infection. It begins with redness and swelling of the cornea. Then a small ulcer appears, which gradually increases in size and seems to creep along the cornea. The ulcer has uneven, corroded edges and a bottom filled with purulent exudate.

The main symptoms are severe pain in the eye, lacrimation, photophobia. When complicated by hypopyon, there is an accumulation of pus in the lower part of the anterior chamber of the eye.

Treatment includes local and general use of antiviral and antibacterial drugs. If conservative therapy is ineffective, surgery may be required.

The prognosis with timely treatment is usually favorable. However, the disease is prone to recurrence and can lead to scarring and decreased vision.



In ophthalmology, corneal tumor is one of the most common eye diseases. In addition, in many patients it occurs simultaneously with cataracts or glaucoma. The corneal-cavernous sinus causes inflammatory edema with the formation of purulent accumulation in front of the lens. The complication leads to decreased visual acuity and loss of adequate perception of the shape and color of objects. Headaches in the orbit, swelling of the eyelids, and redness of the conjunctiva occur.

One of the most difficult cases of corneal ulcer was the protrusion of a rod through the cornea, damaging the inner lining of the eye. Lesions also develop due to microbial infection, metabolic disorders (for example, diabetes mellitus), diseases of the musculoskeletal system, malignant tumors, collagenoses of connective tissue. The causes include injury, irradiation, introduction of foreign substances into the eye tissue, or stimulation of histiocytes of various origins under the influence of toxic substances.