Gilbert's syndrome (from 250 years old), intestinal microligament is a hereditary, quite common (up to 4% of the world's population), polysymptomatic liver disease. Mostly people of Negroid and Semitic races are affected. In recent years, people of white race have become more likely to get sick (8–13% in Europe and North America). According to various sources, there is an increase in the incidence of the disease in our country. A description of the syndrome is available in the National Guide to Gastroenterology.
A triad of skin signs is characteristic (subicteric skin and mucous membranes, telangiectasia and “Biermer’s spots”), urticaria, predominantly edematous syndrome, less often dyspeptic - gastroesophageal reflux, intestinal upset, constipation, disorders of the biliary system (along with these syndromes, others may appear - especially acholic changes in feces, hepatosplenomegaly, anorexia, epilepsy, psychosis). Sometimes there are cases of “anicteric” course of the disease. The main role in the emergence