Acropathy Ulcerative-Mutilating Deforming

Ulcerative mutilating deforming acropathy: symptoms, causes and treatment methods

Acropathy ulcerative mutilating deforming (AMMD) is a rare disease characterized by damage to the bones, skin and soft tissues of the extremities. It is also known as "Bazin-Chaulier disease" after the French doctors who first described its symptoms in 1922.

Symptoms of AIMD may include:

  1. Thickening of the skin on the tips of the fingers and toes, which can lead to loss of sensation.
  2. Formation of ulcers and ulcers on the skin, which can be deep and painful.
  3. Deformations of the bones of the extremities, especially in the area of ​​the hands and feet.
  4. Limitation of mobility and functionality of the limbs.

The causes of AYMD are unknown, but it is believed that the disease may be associated with a disorder of the immune system. It is also believed that genetic factors may play a role in the occurrence of AIMD.

The diagnosis of AYMD can be difficult due to the rarity of the disease and the nonspecificity of its symptoms. It may include computed tomography, magnetic resonance imaging, biopsy and other research methods.

Treatment for AYMD is aimed at reducing pain, preventing further development of deformities and ulcers, and improving the patient's quality of life. Doctors may prescribe anti-inflammatory drugs, antibiotics, immunomodulatory drugs, and other therapies depending on the patient's condition.

Although AYMD is a rare disease, understanding its symptoms and treatment can help doctors make more accurate diagnoses and provide effective treatment for patients. If you suspect AYMD, see your doctor for further evaluation and treatment.



**Acropathy** is a complex multifactorial disease characterized by damage to the skin on the hands and feet due to degeneration of the soft tissues of the extremities.

External manifestations: thickening, soreness, peeling of the skin, formation of abscesses and ulcers. Acropathic lesions are symmetrical and unilateral, localized in the area of ​​the soles, nail phalanges, and palms. Clinical variants include verrucous and panscleritic skin deformities. Acropathy refers to multifactorial diseases, provoked by a combination of internal disorders of the body and extravascular changes. Inflammatory processes affecting the metabolic structures of connective tissue are the main pathogenesis of acropathy. The development of morphological skin disorders depends on age and the strength of vascular reactions. During the aging process, a series of nonspecific reactions of the body begin, ultimately leading to damage to tissue structures. This period is characterized by increased bleeding of blood vessels and a tendency to ulcerative lesions of their walls. In people who have suffered radiation, chemical or mechanical trauma, the likelihood of developing acropathic hypertrophy of the dermis increases significantly. Complications of the process with osteodystrophy, diabetes mellitus, and traumatic cuts aggravate the clinical picture of the disease. Most often, acropania deforms the limbs, manifested by ulcers, plaques, changes in the color of the epidermis, and swelling. As degenerative processes grow, pain during movement increases, tremors of the hands increase, the skin becomes dull, and pigmentation changes. Some variants of the disease have necrotic changes in the skin of the hand, provoked by atherosclerosis, endarteritis, and impaired hemostasis.