Erythema of the palms and soles, hereditary

Erythema palms and soles, also known as hereditary erythema palms and soles (erythema palm-mare et plantare hereditarium), is a rare genetic disorder that is characterized by the appearance of red spots or redness on the palms and soles. This condition is usually inherited and can appear from early childhood.

Hereditary erythema of the palms and soles usually appears as reddish, pinkish, or red-brown patches on the palms and soles. These spots can vary in size and shape, and their color can vary from pale pink to deep red. Sometimes they may be accompanied by slight peeling of the skin.

The reason for the development of hereditary erythema of the palms and soles is still not fully understood. However, it is known that this genetic disorder is associated with a mutation in a specific gene. The inheritance pattern is autosomal dominant, meaning that children with an affected parent have a 50% risk of developing the condition.

Symptoms of hereditary erythema of the palms and soles usually appear in early childhood and can persist throughout life. However, for some people, symptoms may decrease or disappear completely as they age.

Erythema of the palms and soles is hereditary and usually does not cause any serious problems or limitations in daily life. However, some people may experience discomfort or a burning sensation in the affected areas of the skin. In such cases, various symptomatic treatment methods may be offered, such as the use of moisturizing creams or gentle urinary baths.

The diagnosis of hereditary erythema of the palms and soles is usually made on the basis of clinical examination and characteristic symptoms. In rare cases, genetic testing may be necessary to confirm the diagnosis.

Although erythema of the palms and soles is hereditary and chronic, it usually does not require specific treatment or medical intervention. Regularly moisturizing your skin and using gentle skin care products can help reduce discomfort and keep your skin healthy.

In conclusion, hereditary erythema of the palms and soles is a rare genetic disorder that is characterized by the appearance of red patches on the palms and soles. It is inherited and usually does not cause serious problems, but may be accompanied by discomfort. Treatment is aimed at relieving symptoms and maintaining healthy skin. If you suspect you have this condition, it is recommended that you see your doctor for diagnosis and advice.



Erythema of the palms and feet (soles), from Latin erythema palmare et plantere, is a symptom in which a change in the color of the skin occurs on both the palms (palma) and the soles of the feet (pedis). As a rule, erythema of the palms is called erythema of the hands or slang erythroderma of the hands. Its etiology is genetic, but in some cases it can be caused by certain diseases.

Hereditary causes of erythema of the palms:

1. Ataxia is a less common genetic disease, or more precisely a form of hereditary neuropathy, manifested by a disorder of motor coordination, of varying severity depending on the severity and prevalence of pathological processes. 2. Rheumatoid arthritis is a systemic disease that affects the connective tissue of the human body and leads to its deformation. Includes about two thousand diseases. It manifests itself as inflammatory processes in the joints (mainly with a reduced level of sensitivity). 3. Gimpler-Streisler syndrome is a hereditary connective tissue disease. Several types of syndrome or connective tissue dystrophies at different times were combined into one disease - Marfan syndrome, first described in the 19th century by the French physician Alphonse Bouveret (Vincent Roux 1886). 4. Polymyositis Segall-Jacklitt syndrome - hereditary syndromes of connective tissue disorders, leading to a limited decrease in the mobility of individual muscle groups, either without a pronounced decrease in motor functions, or with a decrease in these functions as they progress. Among them, we highlight the two most famous syndromes: Olhas-Dobrino disease, Becker-Sigalov-Jacquelitt syndrome (chorea syndrome - Thurn-Itzschmann-Hardenburg syndrome). 5. Schlumberger's is a rare hereditary and acquired rare genetic multisystem degenerative neuromuscular disease characterized by severe pain in the extremities and a rapid decrease in muscle mass with atrophy of muscle fibers and death of nerve cells. In rare cases, patients develop ataxia, respiratory dysfunction, hormonal changes, and seizures. The viral nature of the disease raises doubts among many researchers. With Strumpell's ataxia, atypical neurofibromatosis can be suspected by a number of indirect signs indicating an increased risk (probability) of this disease. These include disorders of the nervous system. Scientists have found that carriage of the NF1 gene is not only increased, but also decreased. Genetic forms of ataxia accompanied by such signs tend to respond better to treatment with interferon alpha. The life prognosis for atypical ataxia is not very good. Due to poor communication between the facial nerves and the brain, many senses are not obvious. Strumpell-Bardenhain disease has an early onset and a slow progression.